Stem cell therapy was not the final frontier of cell therapy. Exosome therapy is now being used to promote cell regeneration, reduce inflammatory processes, enhance immune modulation and improve cell-to-cell signaling. If you are suffering from an autoimmune disease, degenerative disease or just symptoms of aging, exosome therapy may be able to help you. At PRMedica Inc. in San Jose del Cabo, MX, we are proud to offer exosome therapy to treat a wide range of degenerative and autoimmune diseases. T
Frequently Asked Questions About Exosomes
1. What Are Exosomes?
Exosomes, or extracellular vesicles, are essentially small bubbles which are released from cells. Specifically, they are released from stem cells and function as shuttles for particular types of protein and genetic information to other cells.
2. What Is Exosome Therapy?
Exosome therapy is a revolutionary type of therapy for a whole host of medical conditions. Research has provided us with the insight that young stem cells are the key to rejuvenating older stem cells. This opens the door for all sorts of regenerative medicine.
3. Can I Benefit From Exosome Therapy?
Exosome therapy is currently being used to treat clients with autoimmune diseases, chronic inflammation, Lyme disease and other chronic degenerative diseases. It is also a valuable component of any anti-aging treatment regimen. If you suffer from degenerative joint disease, we strongly recommend that you contact us to see if exosomes can help improve your quality of life.
4. How Is Therapy Performed?
Exosome therapy is performed by administering an IV push or IV treatment. In the case of joint rejuvenation therapy, exosomes are directly administered into the affected joint region. The typical concentration used includes 1 billion extracellular vesicles per milliliter. However, depending on the severity of your case, your treatment may contain up to 15 billion extracellular vesicles per milliliter.
Each dose is unique to the client, the type of medical condition she is trying to address and the severity of her condition. In some instances, exosome therapy is complemented with regional hypothermia, frequency therapy, or focused ultrasound to encourage the extracellular vesicles to travel to a particular part of the body.
5. What Can I Expect After Treatment?
This treatment is performed on an outpatient basis. This means you can go back to your hotel and enjoy the rest of your stay in Mexico after your therapy. There is no downtime or discomfort associated with this treatment. No long-term side effects have been reported.
6. What After-Care Instructions Do I Need to Follow?
To enjoy the best results from this treatment, avoid taking anti-inflammatory medications immediately after this treatment. Avoid strenuous activity for the first 24 to 48 hours. Wait three to four weeks before resuming cardiovascular workouts. If you feel the need to work out, perform anaerobic exercises in the meantime. After four weeks, you can resume running and heavy weight lifting.
7. Is Exosome Therapy Safer Than Stem Cell Therapy?
Whether exosome therapy or stem cell therapy is right for you depends on what you are trying to accomplish. At PRMedica, you are in good hands no matter which method you choose to use. However, we’d like you to know that we are using the latest techniques in biocellular regenerative medicine to complement our stem cell therapies and achieve some of the best results in the world.
By synergizing the best parts of stem cell treatments and exosome therapy, you may find that the best treatment for your degenerative disease is a combination of the two therapies.
8. Could My Body Reject the Extracellular Vesicles?
It’s important to understand that exosome cells are not tissue or cells. Because there are no immune markers on the surface of extracellular vesicles, your body will not reject them as a foreign substance.
9. Can They Form Teratomas?
Exosome cells are not embryonic stem cells and cannot form teratomas. They cannot multiply. Rather, they transfer essential biological signals to your tissues and promote the normalization of various critical functions.
10. How Long Do They Work?
Exosomatic cells trigger what is known as a bi-phasic response. First, they produce an immediate reaction that lasts around 24 hours. The day after your treatment, the initial proteins will have degraded. Over the course of the next six to eight weeks, the messenger RNA inserted into the target cells activates and helps to “reprogram” the cell.
In some cases, it can take eight to 10 weeks for exosome therapy to work. However, you will feel the effects of treatment for several months after your initial session.
11. Can Exosome Therapy Help People With Chronic Infections?
Chronic infections are extremely similar to autoimmune disease. Chronic infections are often characterized by a dysregulated immune response that causes the body to attack its own organs and tissues while allowing pathogens (molds, viruses, bacteria) to wreak significant structural damage.
Exosome therapy is so effective at controlling your body’s immune responses because it strikes an essential balance between the immune cells responsible for autoimmune responses and pathogen protection. In other words, it impacts the Treg to Th17 ratio. Our exosome cells are derived from mesenchymal stem cells. These are proven to normalize the ration between Treg and Th17 immune cells and normalize the deviant immune response.
12. How Can Exosome Therapy Help People With Neurodegenerative Diseases?
Exosome therapy helps people with neurodegenerative diseases, like Alzheimer’s disease, because it is able to penetrate the blood-brain barrier. Once this penetration occurs, it stimulates neuronal differentiation and neuronal growth while suppressing your brain tissue’s inflammatory processes.
13. How Does Exosome Therapy Improve Chronic Inflammation?
Exosome cells derived from stem cells have anti-inflammatory properties. Moreover, they promote the production of anti-inflammatory cytokines which further assists the regulation of your body’s inflammatory response.
Exosome cells also inhibit the activation of abnormal macrophage. Macrophage refers to large white blood cells that make up an essential component of our immune system. The job of macrophage is to identify microscopic foreign bodies and consume them. Painful inflammatory responses, from topical dermatitis to knee pain, result from disproportional macrophage activation.
14. Can Exosome Therapy Cause Cancer?
Exosome therapy cannot cause cancer growth. On the contrary, research is currently being performed on exosomes derived from stem cells to test if exosome therapy can be used to stop the spread of cancer.
15. How Many Rounds of Treatments Will I Need?
Each case of exosome therapy is unique. Some of our clients may find their treatment takes 10 weeks to produce final results and the effects only last nine months. In other cases, you might see results after only a month-and-a-half but experience no inflammatory flare-ups for a year after treatment starts working.
During your initial consultation, we will assess your condition and help you determine the best dosing schedule for your unique needs. For example, you may need a small initial dose followed by doses that become increasingly large over time. Alternatively, you may need several booster doses or only need one application.
16. Are All Exosomes the Same?
Not all exosome cells are the same. Our exosome therapy solution is produced with placental-derived mesenchymal stem cells. These have been screened and certified for safety and efficacy. The final product contains both immune modulatory proteins and anti-inflammatory cytokines. If you have a medical condition that won’t respond to other therapies, exosome therapy may be right for you.
The type of exosome used for your therapy will depend on your unique case. Sometimes, we use a client’s own tissue to provide us with certain markers to combine with manufactured exosome cells. In addition to this, several techniques may be used to attract the exome cells to the parts of the body that need to be treated.
17. How Does Exosome Therapy Affect Lyme Disease?
Lyme Disease is a highly complex disease characteristic of a compromised immune system. It is caused by a type of bacteria known as Borrelia burgdorferi. This tick-borne disease often comes with several infections at once. The combination of all these pathogens results in the disruption of crucial immune system functions.
You may notice your metabolism and energy levels drop. You may suffer from severe inflammation of the joints or skin. Most importantly, you may suffer from the symptoms of a compromised immune system and diminished cellular health.
Exosome therapy helps people with Lyme Disease in that it helps to break the inflammatory cycle caused by a dysfunction in the mast cells. As part of a multi-modality treatment regimen, exosome therapy can give your body the time and tools it needs to finally start healing.
18. Can Exosome Therapy Treat or Reverse COPD?
COPD, or chronic obstructive pulmonary disease, is the fourth-leading cause of death in the world. Researchers at the University of Alabama at Birmingham discovered a novel link between the lung tissue destruction of people with COPD and chronic inflammation.
This study reported in the scientific journal Cell remarks that there are other diseases affected by tissue destruction and immune cell inflammation. These include chronic kidney disease, metastatic cancer, and heart attacks.
So, what does research performed at an Alabama university have to do with exosome therapy? The answer may be everything. Exosome cells harbor protease enzymes that attack harmful microbes and protect tissue from damage.
19. How Can EV Treat OA?
Extracellular vesicles manage osteoarthritis symptoms by promoting cross-talk between the cells in your joint tissues, managing your body’s inflammatory response and stimulating extracellular matrix turnover. Studies show that extracellular vesicles can even eliminate pain caused by abnormal mineralization.
20. Is Exosome Therapy the Best OA Treatment?
The best osteoarthritis treatment for people who do not want an invasive medical procedure performed is a combination of stem cell and extracellular vesicle therapy. At PRMedica Inc., your recovery process begins with an initial consultation and focused orthopedic assessment. Your physician will run a full blood panel on you, as well as MRI, ultrasound, or x-ray imaging to determine if you are a viable candidate for this treatment method.
We may recommend a series of ozone therapy sessions to ease pain, minimize swelling and treat soft tissue injuries before your exosome therapy. This will relax your body, making it more receptive to healing. It also helps to direct the exosome cells to the necessary tissue that needs replacement or repair.
Once the treatment site is ready, the attending physician will administer the ideal dosage of mesenchymal stem cells and exosome cells. This will be based on the type and severity of your medical condition. Each syringe is mixed with your own oxygenated PRP that is centrifuged on the day of your treatment. This customized mix infuses the joint with even more healing power, anti-inflammatory properties, and regenerative potential.
Learn More About Regenerative Medicine Today
To learn more about exosomes or any other cutting-edge regenerative treatment, call PRMedica Inc. in Cabo San Lucas, MX today to schedule your initial consultation.